Clinical Software Infrastructure

Where Validated Science Meets Scalable Software

Lifeline Medical Technologies engineers precision clinical decision support software designed to resolve operational workflow errors at the point of care, delivering data-driven confidence to the bedside.

Core Operations

Venture Portfolio

Three operational divisions converging clinical validation, software engineering, and systems design into a unified infrastructure for safer care.

Precision Analgesia Platform

The flagship clinical decision support platform of Lifeline Medical Technologies pairs a live native iOS application — currently in TestFlight beta — with an enterprise EHR integration pathway built on SMART on FHIR and CDS Hooks. A 10-rule deterministic safety engine, derived from the PRODIGY trial and CDC 2022 Clinical Practice Guidelines, intercepts high-risk opioid orders at the moment of signing.

Every recommendation is glass-box transparent: clinicians can independently verify the arithmetic behind each dose via a traceability ledger, satisfying FDA Non-Device CDS criteria under the 21st Century Cures Act. A zero-PHI, in-memory architecture eliminates data-breach surface entirely. Physician-led clinical validation is advancing through an addiction medicine fellowship pathway beginning July 2026.

iOS NativeSMART on FHIRCDS HooksDeterministic EngineFDA Non-Device CDSZero-PHI ArchitectureCDC 2022 ValidatedAddiction Medicine Validated
Visit Product SiteTry the Live Taper Engine Demo

Deterministic Rule Engine

Order interception logic

Verified
10clinical rules

iOS Clinical Beta

TestFlight distribution

Live
v11.2shipping
CDC Clinical Practice Guideline for Prescribing Opioids for PainPrimary evidence base for all MME conversion factors, 90 MME/day dose threshold (SR-1), naloxone co-prescribing recommendation (SR-9), and taper protocols.
2022
PRODIGY Trial — Khanna AK et al., Anesthesia & AnalgesiaDerivation cohort for the PRODIGY opioid-induced respiratory depression risk score (SR-8). 46% of inpatients on parenteral opioids experienced respiratory depression events on continuous monitoring.
2020
AGS Beers Criteria for Potentially Inappropriate Medication Use in Older AdultsEvidence base for geriatric opioid caution threshold (SR-7, age ≥ 65) and renal-clearance considerations (SR-5).
2023
ASAM Clinical Practice Guideline for Treatment of Opioid Use DisorderGuideline basis for OUD consultation module: COWS threshold for buprenorphine induction, low-dose (Bernese) protocol, and precipitated withdrawal risk flagging.
2020
FDA Black Box Warning — Opioid and Benzodiazepine Co-prescribingMandatory labeling warning basis for SR-2 (concurrent benzodiazepine + opioid advisory). Concomitant use increases risk of respiratory depression, coma, and death.
2016
FDA Guidance on Clinical Decision Support SoftwareNon-Device CDS classification under 21st Century Cures Act §3060(o)(1)(E): deterministic, transparent, clinician-overridable logic exempt from 510(k) premarket review.
2022
Joint Commission Sentinel Event Alert: Safe Use of Opioids in HospitalsInstitutional opioid safety requirements including dose threshold monitoring, respiratory risk screening, and naloxone availability standards.
2024

Dual Management Protocol

Strategic Leadership

Lifeline Medical Technologies operates under a co-managed governance framework, distributing executive authority across clinical and technical domains.

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Daniel R. Bergholz, MD

Chief Executive Officer & Founder

Dr. Bergholz directs clinical medicine validation, software safety compliance, and evidence-based design standards across all Lifeline product lines. An incoming Addiction Medicine Fellow at Yale School of Medicine (July 2026) — the clinical domain at the core of the Precision Analgesia platform — his oversight ensures that every algorithm, dosing model, and safety threshold traces directly to peer-reviewed clinical evidence.

Yale Addiction MedicineClinical ValidationSafety ComplianceEvidence-Based Design
JA

Joseph M.V. Amari, Esq.

Chief Legal Officer

Mr. Amari directs legal affairs, regulatory compliance, and corporate governance for Lifeline Medical Technologies. His strategic mandate ensures all product development aligns with federal healthcare regulations, intellectual property laws, and data privacy requirements.

Regulatory ComplianceCorporate GovernanceIntellectual PropertyData Privacy
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Thomas Mulc

Chief Technology Officer

Mr. Mulc manages infrastructure development, technical engineering, and system launch logistics for Lifeline Medical Technologies. His operational mandate covers the full product lifecycle from architecture planning through deployment, scaling, and continuous integration.

InfrastructureTechnical EngineeringLaunch LogisticsSystem Architecture